ADRC Best Practices

In 2020-2021, the National Institute on Aging convened a working group (Contributors) to update the guidance on best practices for the ADRCs in the acquisition, preparation, and storage of biospecimens. These updated documents are included below by topic, along with best practice recommendations for other areas. The recommendations for annual ADRC External Advisory Committee meetings, which also may be of assistance in preparing ADRC Progress Reports, were developed in 2017.

These best practices are intended to be a resource for new Centers and for Centers who may be embarking on a new line of research. Of importance, they should not be construed as requirements for Center activities.

We appreciate that many of these areas are rapidly evolving and as such, we envision these guidelines as dynamic and will be re-evaluated periodically to determine if further updates are needed.The updated and new guidance will be posted on the Updated Guidance Page. Please email Dr. Krista Moulder ( if you have suggestions for new topics or for sections that may be outdated.

Note: We are following DOI Best Practices for a collection of documents.

Brain*Consent / Confidentiality*
Cost Recovery*Digital Neuropathology*
DNA / RNA / Protein*EAC Guidelines*
Informatics*Intellectual Property*
Material Transfer*Guidance for Management and Sharing
Rigor and Reproducibility
Digital Voice CaptureRemuneration
Biomarker Disclosure
Metabolomics / Proteomics
Disseminating / Discarding
Recruitment Planning GuideNational Strategy

*Included in the original working group guidance. A single PDF of the collected working group guidance is available for reference here.