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National Alzheimer's Coordinating Center
National Alzheimer's Coordinating Center
The NIA Alzheimer’s Disease Research Centers Program
National Alzheimer’s Coordinating Center

Data Front Door

The NACC Data Front Door (DFD) empowers researchers to rapidly search, visualize, and access ADRC participant data across modalities and repositories to access the pace of discovery in AD/ADRD.

The DFD offers streamlined access to a growing volume and variety of standardized and harmonized multimodal data from over 54,000 participants. Key components of the DFD include our streamlined Quick Access File Data Request System (powered by REDCap), real-time dashboards, secure LINKAGE enclave, and our new multimodal query tool (MQT). The DFD is enabling researchers to ask and answer new questions and to tackle the most pressing challenges in the field, including through AI-driven discovery.

Data Front Door Schematic

Learn more about the data modalities available via the DFD:

Quick Access File Data Request System (QAF-DRS)

Rapid access to NACC’s high-quality data. It takes just 15 minutes to sign a DUA and submit a request through our electronic system. Approved researchers will receive all data within 48 hours (not including weekends and holidays).

Submit Data Request

Real-time dashboards

Dynamic insights into data availability. The SCAN Public Dashboard provides researchers with up-to-date information on the volume of standardized MRI/PET data (SCAN-compliant) and analysis results that are available from across the ADRC Program.

See image data availability

LINKAGE Enclave

Approved researchers at pilot project partner sites can now access and perform analysis on integrated UDS, real-world data (EHR and claims), and genetic data (Genome-Wide Association Studies (GWAS), Whole Exome Sequencing (WES), Whole Genome Sequencing (WHS)) within a secure enclave.

Email us to find out more

Multimodal Query Tool (MQT)

MQT Schematic

The Multimodal Query Tool is a self-service tool designed to empower researchers to:

  • Rapidly assess whether the available data is a good match for their research question and/or proposed analysis. Researchers can instantly build and visualize their own multimodal datasets in real-time and determine sample size!
  • More easily search and access a large volume and variety of multimodal data for ADRC participants across different AD/ADRD repositories (e.g. NACC, NCRAD, NIAGADS, ADKP, LONI, and others)
  • Monitor the sample size of NACC participants meeting your eligibility criteria in real-time
  • Download the NACCIDs for your selection and access all data available for participants via NACC and partner repositories
  • Access a reproducible record of your MQT sample to use as a citation in publication
Click here to view the MQT prototype